Program

・・・・・・・・・・・・Monday, October 29・・・・・・・・・・・・

Registration

8:00-

Opening Remarks

8:45-9:00	Kohei Miyazono (The University of Tokyo, Japan)

Session 1. TGF-β Signaling

Chair: Keiji Miyazawa (University of Yamanashi, Japan)

9:00-9:30	Maréne Landström (Umeå University, Sweden) TGFβ and TRAF6-dependent cleavage and nuclear translocation of TGFβ type I receptor promotes invasion of cancer cells
9:30-10:00	Susumu Itoh (Showa Pharmaceutical University, Japan) Negative regulation of TGF-β signaling
10:00-10:30	Carl-Henrik Heldin (Uppsala University, Sweden) Signaling via TGFβ receptors
10:30-11:30	Poster Viewing1 / Coffee Break
11:30-12:00	Takeshi Imamura (Ehime University, Japan) Advanced in vivo fluorescent imaging for cancer research

Special Lecture 1

Chair: Carl-Henrik Heldin (Uppsala University, Sweden)

12:00-12:40	Hidenori Ichijo (The University of Tokyo, Japan) SOD1 as a molecular switch to initiate the homeostatic ER stress response
12:40-12:55	Group Photo
12:55-14:00	Lunch

Session 2. Tumor Microenvironment

Chair: Hideyuki Beppu (University of Toyama, Japan)

14:00-14:30	Atsushi Kaneda (The University of Tokyo, Japan) Coordinated epigenomic regulation of Bmp2-Smad1 signal in oncogene-induced cellular senescence
14:30-15:00	Peter ten Dijke (Leiden University, the Netherlands) USP4 directly deubiquitylates TGF-β type I receptor
15:00-15:30	Shigeki Higashiyama (Ehime University, Japan) The role of ectodomain shedding in an EGFR/ ligand signaling system
15:30-16:30	Poster Viewing 2 / Coffee Break

Special Lecture 2

Chair: Peter ten Dijke (Leiden University, the Netherlands)

16:30-17:10	Ye-Guang Chen (Tsinghua University, Beijing) Regulation of TGF-β receptor stability by PICK1

Session 3. Short talks 1 (selected from poster abstracts)

Chair: Marie-José Goumans (Leiden University, the Netherlands)

17:10-17:30	Katsunori Yoshida (Kansai Medical University) (Poster 01)
17:30-17:50	Thanh Thao Vo Nguyen (University of Tsukuba) (Poster 02)
17:50-18:10	Makiko Fujii (Aichi Cancer Center Research Institute) (Poster 04)

Banquet

18:30-20:30	Showa Pharmaceutical University

・・・・・・・・・・・・Tuesday, October 30・・・・・・・・・・・・

Registration

8:00-

Session 4. Short talks 2 (selected from poster abstracts)

Chair: Maréne Landström (Umeå University, Sweden)

9:00-9:20	Shingo Maeda (Kagoshima University) (Poster 07)
9:20-9:40	Akiyoshi Komuro (The University of Tokyo) (Poster 18)
9:40-10:00	Erna Raja (Uppsala University) (Poster 19)
10:00-10:30	Poster Viewing 3 / Coffee Break

Session 5. Cardiac and Vessel Development

Chair: Fumiko Itoh (Tokyo University of Pharmacy and Life Sciences, Japan)

10:30-11:00	Marie-José Goumans (Leiden University, the Netherlands) MicroRNA 155 is a regulator of TGF-β induced endothelial to mesenchymal transition and cardiac stem cell behaviour
11:00-11:30	Kyoko Hida (Hokkaido University, Japan) Altered phenotype in endothelial cells in tumor microenvironment

Special Lecture 3

Chair: Mitsuyasu Kato (University of Tsukuba, Japan)

11:30-12:10	Naoya Fujita (Cancer Chemotherapy Center, Japan) The role of tumor-platelet interaction in hematogenous metastasis

Closing Remarks

12:10-12:20	Peter ten Dijke (Leiden University, the Netherlands)